Evergreen Youth Secrets
  • Health News
  • Health Care
  • Staying Healthy
  • Beauty Advices
  • Health News
  • Health Care
  • Staying Healthy
  • Beauty Advices
No Result
View All Result
Evergreen Youth Secrets
No Result
View All Result
Home Health Care

Pfizer will end development of daily anti-obesity pill due to liver injury

by
April 14, 2025
in Health Care
0
Pfizer will end development of daily anti-obesity pill due to liver injury

Pfizer is stopping development of its experimental oral GLP-1 drug for obesity, the company announced Monday, after a patient in a trial suffered a liver injury potentially caused by the drug. 

The patient did not experience any symptoms, and the injury resolved after discontinuation of the drug, Pfizer said in a statement. After reviewing all clinical data for the medicine and consulting with regulators, Pfizer said it decided to halt research on it. 

The case occurred in a “doze optimization” trial, aimed at finding the highest tolerable dose in a short amount of time. 

“While we are disappointed to discontinue the development of danuglipron, we remain committed to evaluating and advancing promising programs in an effort to bring innovative new medicines to patients,” said Chris Boshoff, Pfizer’s chief scientific officer and president of research and development. 

Boshoff said Pfizer is going to continue development of another other weight loss drug, called a GIP antagonist.  

Still, the company said its drug met key trial objectives and “confirmed a formulation and dose with the potential to deliver a competitive efficacy and tolerability profile in Phase 3 testing.” 

The company added that the overall frequency of liver enzyme elevations across the 1,400-participant safety database of the medicine was in line with other medicines in the class. 

Pfizer’s decision is a setback for the company, which had been trying to win a share of the booming GLP-1 market dominated by blockbuster drugs Wegovy and Zepbound from rivals Novo Nordisk and Eli Lilly respectively.  

Pfizer previously discontinued a twice-daily version of the pill in December 2023 after patients had trouble tolerating the drug in a mid-stage study.  

GLP-1 drugs can cause substantial weight loss, but they are delivered by injection, making them more difficult to manufacture. They have also faced demand-induced shortages. Oral drugs are easier to make and would be more widely available, though Pfizer’s was not as effective as other experimental oral drugs.  

Previous Post

RFK Jr. claims new research effort will find cause of ‘autism epidemic’ by September

Next Post

7 US service members had ‘COVID-19-like symptoms’ after 2019 Wuhan games: Pentagon report

Next Post
7 US service members had ‘COVID-19-like symptoms’ after 2019 Wuhan games: Pentagon report

7 US service members had ‘COVID-19-like symptoms’ after 2019 Wuhan games: Pentagon report

Stay updated with the latest news, exclusive offers, and special promotions. Sign up now and be the first to know! As a member, you'll receive curated content, insider tips, and invitations to exclusive events. Don't miss out on being part of something special.

    Popular News

    New Hampshire lawmakers give final approval to gender-affirming care ban 

    New Hampshire lawmakers give final approval to gender-affirming care ban 

    June 27, 2025
    FDA expanding COVID vaccine warnings over rare heart side effect

    FDA expanding COVID vaccine warnings over rare heart side effect

    June 27, 2025
    Supreme Court upholds HHS authority over ObamaCare preventative care task force

    Supreme Court upholds HHS authority over ObamaCare preventative care task force

    June 27, 2025

    Trending

    Trump voices support for RFK Jr.’s vaccine views, suggests Kennedy will research debunked autism link

    Trump voices support for RFK Jr.’s vaccine views, suggests Kennedy will research debunked autism link

    December 9, 2024
    Eli Lilly lowering weight loss drug prices

    Eli Lilly lowering weight loss drug prices

    August 27, 2024
    Dr. Sanjay Gupta: Blockbuster weight loss drugs are revealing what we still don’t understand about obesity

    Dr. Sanjay Gupta: Blockbuster weight loss drugs are revealing what we still don’t understand about obesity

    November 16, 2024
    Between bright light and a good mood, plenty of sleep

    Between bright light and a good mood, plenty of sleep

    August 7, 2024

    Recent News

    New Hampshire lawmakers give final approval to gender-affirming care ban 

    New Hampshire lawmakers give final approval to gender-affirming care ban 

    June 27, 2025
    FDA expanding COVID vaccine warnings over rare heart side effect

    FDA expanding COVID vaccine warnings over rare heart side effect

    June 27, 2025

    Popular News

    • New Hampshire lawmakers give final approval to gender-affirming care ban 
    • FDA expanding COVID vaccine warnings over rare heart side effect

    About Evergreen Youth Secrets

    • Contact us
    • Privacy Policy
    • Terms & Conditions
    • Email Whitelisting

    Copyright © 2025 Evergreenyouthsecrets.com. All Rights Reserved.

    No Result
    View All Result
    • Health News
    • Health Care
    • Staying Healthy
    • Beauty Advices

    Copyright © 2025 Evergreenyouthsecrets.com. All Rights Reserved.